18 Types of Spanish Verbs

18 Types of Spanish Verbs There may be as many ways of classifying Spanish verbs as there are people doing it, but discovering how Spanish treats different verbs differently is nevertheless a key part of learning the language. Heres one way of looking at the types of verbs, keeping in mind, of course, that verbs can fit into more than one classification. 1. Infinitives Infinitives are verbs in their most basic form, the way you find them listed in dictionaries. Infinitives by themselves tell you nothing about who or what is performing a verbs action or when. Spanish infinitives- examples include hablar (to speak), cantar (to sing), and vivir (to live)- are the rough equivalent of the to form of English verbs and sometimes of the -ing form. Spanish infinitives can function as verbs or nouns. 2, 3, and 4. -Ar, -Er, and -Ir Verbs Every verb fits into one of these types based on the last two letters of its infinitive. In Spanish there is no verb that ends in anything other than one of these three two-letter combinations. Even verbs that are made up or imported such as surfear (to surf) and snowboardear (to snowboard) require one of these endings. The distinction among types is that they are conjugated based on the ending. 5 and 6. Regular and Irregular Verbs The vast majority of -ar verbs are conjugated in the same way, and the same is true for the other two ending types. These are known as regular verbs. Unfortunately for Spanish students, the more used a verb is, the more likely it is not to follow the regular pattern, being irregular. 7 and 8. Defective and Impersonal Verbs The term defective verb is usually used to refer to a verb that isnt conjugated in all its forms. In traditional Spanish, for example, abolir (to abolish) has an incomplete conjugation set. Also, soler (to usually do something) doesnt exist in all tenses. Most defective verbs are also impersonal verbs, meaning that their action isnt performed by a distinct person or thing. The most common such are the weather  verbs such as llover (to rain) and nevar (to snow). Since theres no logical reason to use forms that mean something like we rain or they snow, such forms dont exist in standard Spanish. 9 and 10. Transitive and Intransitive Verbs The distinction between transitive and intransitive verbs is important enough to Spanish grammar that the classification is given in most Spanish dictionaries- vt or vtr for verbos transitivos and vi for verbos intransitivos. Transitive verbs require an object to make a complete sentence, while intransitive verbs do not. For example, levantar (to lift or raise) is transitive; it must be used with a word that indicates what is lifted. (In Levantà ³ la mano for He raised his hand, mano or hand is the object.) An example of an intransitive verb is roncar (to snore). It cannot take an object. Some verbs can be transitive or intransitive depending on the context. Most of the time, for example, dormir is intransitive, as is its English equivalent, to sleep. However, dormir, unlike to sleep, can also mean to put someone to sleep, in which case it is transitive. 11. Reflexive or Reciprocal Verbs A reflexive verb is a type of transitive verb in which the verbs object is also the person or thing performing the action of the verb. For example, if I put myself to sleep, I could say, Me durmà ­, where durmà ­ means I put to sleep and me means myself. Many verbs that are used in a reflexive way are listed in dictionaries by adding -se to the infinitive, creating entries such as dormirse (to fall asleep) and encontrarse (to find oneself). Reciprocal verbs take the same form as reflexive verbs, but they indicate that two or more subjects are interacting with each other. Example: Se golpearon uno al otro. (They beat up on each other.) 12. Copulative Verbs A copulative or linking verb is a type of intransitive verb that is used to connect the subject of a sentence with a word that describes it or says what it is. For example, the es in La nià ±a es guatemalteca (The girl is Guatemalan) is a linking verb. The most common Spanish linking verbs are ser (to be), estar (to be), and parecer (to seem).  Verbs that arent copulative are known in Spanish as verbos predicativos. 13. Past Participles A past participle is a type of participle that can be used to form the perfect tenses. Most past participles end in -ado or -ido. As in English, past participles can also usually be used as adjectives. For example, the past participle quemado , from the verb quemar, meaning to burn, helps form the present perfect tense in He quemado el pan (I have burnt the bread) but is an adjective in No me gusta el pan quemado (I dont like burnt bread). Past participles can vary in number and gender like other adjectives. 14. Gerunds Present adverbial participles, often known as gerunds, end in -ando or -endo as the rough equivalent of English -ing verb forms. They can combine with forms of estar to make progressive verb forms: Estoy viendo la luz. (I am seeing the light.) Unlike other types of participles, Spanish gerunds can also function much like adverbs. For example, in Corrà © viendo todo (I ran while seeing everything), viendo describes how the running occurred. 15. Auxiliary Verbs Auxiliary or helping verbs are used with another verb to give it vital meaning, such as a tense. A common example is haber (to have), which is used with a past participle to form a perfect tense. For example, in He comido (I have eaten), the he form of haber is an auxiliary verb. Another common auxiliary is estar as in Estoy comiendo (I am eating). 16. Action Verbs As their name suggests, action verbs tell us what someone or something is doing. The vast majority of verbs are action verbs, as they include the verbs that arent auxiliary verbs or linking verbs. 17 and 18. Simple and Compound Verbs Simple verbs consist of a single word. Compound or complex verbs use one or two auxiliary verbs and a main verb and include the perfect and progressive forms mentioned above. Example of compound verb forms include habà ­a ido (he has gone), estaban estudiando (they were studying), and habrà ­a estado buscando (she will have been seeking). 10, 20, and 21. Indicative, Subjunctive, and Imperative Verbs These three forms, known collectively as referring to a verbs mood, indicate the speakers perception of a verbs action. Simply put, indicative verbs are used for matters of fact; subjunctive verbs often are used to refer to actions that the speaker desires, doubts or has an emotional reaction to; and imperative verbs are commands.

A Brief Timeline of Events in America - 1626 - 1650

A Brief Timeline of Events in America - 1626 - 1650 1626 Peter Minuit arrives in New Netherland and later buys Manhattan from the Native Americans for items worth approximately $24. He then names the island New Amsterdam. 1627 Plymouth Colony and New Amsterdam begin trading.A shipload of approximately 1500 kidnapped children is sent from England to the Virginia colony to increase the number of settlers in the colony. 1628 A group of settlers led by John Endecott settles at Salem. This begins the Massachusetts Bay Colony. 1629 The Massachusetts Bay Colony is given a royal charter.The Dutch West India Company begins to give land grants to patrons who will bring at least 50 settlers to the colonies.John Winthrop is elected the governor of the Massachusetts Bay Colony.King Charles I grants Sir Robert Heath a territory in North America that is to be called Carolina. 1630 John Winthrop leads over 900 colonists to settle in the Massachusetts Bay Colony.John Winthrop also begins writing the History of New EnglandBoston is officially established.William Bradford, Governor of Plymouth colony, begins writing History of Plymouth Plantation. 1631 Despite the Massachusetts Bay Colony charter, it is decided that only church members are allowed to become freemen who are allowed to vote for colony officials.Sir Ferdinando Gorges is given a land grant and begins to settle what will eventually become Maine. 1632 In the Massachusetts Bay Colony issues such as no taxation without representation and representative government are beginning to be addressed.King Charles I grants Lord Baltimore a royal charter to found the Maryland Colony. Since Baltimore is Roman Catholic, the right to religious freedom is granted to Maryland. 1633 The first town government is organized in the city of Dorchester within the Massachusetts Bay Colony.The first school in America is founded in New Amsterdam. 1634 The first settlers for the new Maryland colony arrive in North America. 1635 Confrontations occur between Virginia and Maryland based on boundary disputes between the two colonies.The charter for the Massachusetts Bay Company is revoked. The colony refuses to yield to this, however.Roger Williams is ordered banished from Massachusetts after criticizing the colony and promoting the idea of separation of church and state. 1636 The Township Act is passed in the Massachusetts Bay general court giving towns the ability to govern themselves to some extent.Thomas Hooker arrives in Hartford Connecticut and founds the first church of the territory.Roger Williams founds the present-day city of Providence, Rhode Island.Open warfare begins with Pequot Indians after the death of New England trader John Oldham.Harvard University is founded. 1637 After numerous encounters, the Pequot Indians are massacred by a force of Connecticut, Massachusetts Bay, and Plymouth colonists. The tribe is virtually eliminated.Anne Hutchinson is banished from the Massachusetts Bay Colony. 1638 Anne Hutchinson leaves for Rhode Island and founds Portsmouth with William Coddington.Peter Minuit dies in a shipwreck. 1639 The Fundamental Orders of Connecticut are enacted.Sir Ferdinando Gorges is named the governor of Maine by royal charter.New Hampshire Colony settlers sign the Exeter Compact. 1640 Dutch colonists settle in the Delaware River area. 1641 Massachusetts Bay Colony takes over the jurisdiction of New Hampshire. 1642 New Netherland fights against the Hudson River Valley Indians who have been making raids against the colony. Both sides will later sign a truce that will last a year. 1643 The New England Confederation, also known as the United Colonies of New England, a confederation of Connecticut, Massachusetts, Plymouth, and New Hampshire, is formed.Anne Hutchinson is murdered by Indians on Long Island. 1644 Roger Williams is granted a royal charter for Rhode Island. 1645 The Dutch and the Hudson River Valley Indians conclude peace after four years of warfare.The New England Confederation sign a peace treaty with the Naragansett Indians. 1646 Massachusetts becomes increasingly intolerant as they pass a law making heresy punishable by death. 1647 Peter Stuyvesant assumes the leadership of New Netherland.Rhode Island General Assembly drafts a constitution allowing for separation of church and state. 1648 The Dutch and the Swedes compete for the land around present-day Philadelphia on the Schuylkill River. They each build forts and the Swedes burn down the Dutch fort twice. 1649 King Charles I of the House of Stuart is excommunicated in England. Virginia sides with the house of Stuart.Toleration Act is passed in Maryland allowing for religious freedom.Maine also passes legislation allowing for religious freedom. 1650 Maryland is allowed to have a bicameral legislature by order of Lord Baltimore.Virginia is blockaded by England after declaring allegiance to the House of Stuart. Source Schlesinger, Jr., Arthur M., ed. The Almanac of American History. Barnes Nobles Books: Greenwich, CT, 1993.

Nellie McClung Essay Example | Topics and Well Written Essays - 1000 words - 1

Nellie McClung - Essay Example ves and today they are recognized as government officials, CEOs, established professionals, sometimes the Head of their household and now have access to certain rights and privileges. Nellie McClung, a Canadian Activist is credited for the progress of the women in today’s Canadian society. She was the voice for the women who didn’t have the privilege to speak and her contribution to fighting for women’s rights is the reason they can obtain white collar jobs and favourable divorce and custody laws. 1She is famous for her superb humoured public speaking and determinant abilities to get women recognized and accepted as individuals who deserve equal rights and other privileges. 2 Nellie Letitia Mooney was a Canadian Feminist, suffragist, social reformer, legislator, author and politician.3 Born in Chatsworth on October 20th 1873, she was raised on a homestead in rural Manitoba and is an inspiration to women everywhere. Her father was an Irish Methodist and her mother a Scottish Presbyterian. Nellie McClung helped to shape the history of women’s rights in Canada. Inspired by Dickens’ novels she decided that she wanted to be the voice for the voiceless as Dickens’ was a defender for the weak. 4Cross referenced literature declared that Mooney started school at the age of 10 but by the age of 16 had received a teaching certificate and taught school, which was a highly respected profession for women at the time, until she wed Robert Wesley McClung, a pharmacist in 1896. The couple had four children and produced a fifth when they relocated to Winnipeg and from all sources seemed to have had a happy and productive marriage. McClung had contributed greatly to Canada actively campaigning for women’s suffrage, safety legislations, prohibition of the sale of alcohol, labour reforms, mother’s allowances, public health nursing, free medical and dental care for children, divorce laws and property rights.5 McClung had a rather extensive career profile; a rural

Impact of Globalization on the country Identity Essay

Impact of Globalization on the country Identity - Essay Example Furthermore, numerous buildings in the city are still designed based on their historical relevance. The impact of globalization has been spread out across different countries all over the world. The world has become more interconnected than ever. Never before in the history has international connections between world trade, communication, and politics been seen at this rate and pace. The responsibilities of planners have also increased with the arrival of globalization and as research indicates, the planning of cities is no longer limited to physical planning, but it now also includes the social and economic fabric (The Role of Planners in the Globalization Era, 2004). The globalization of economic, social, environment and political matters have not been limited to the national level, but have now also affected the urban and architectural planning of the city. Globalization is a term used by a development and interaction process of international union arising from the networking of world views, products, ideas and other aspects of culture. Advances in transportation and telecommunications infrastructure are major factors in globalization, generating further interrelationships of economic and cultural activities (Globalization, 2014). In the globalized world, geography does not become less important, instead it has become more relevant. This is because of the fact that globalization enhances possibilities in increasing geographic differentiation and location which then reflect on overall planning. The globalization extends a large group and city regions outside their borders. The internal and external of these cities and their growth present a number of challenges for policy makers in their planning. Based on the history of urban planning in Qatar, changes in planning can be recognized. In 1935, British petroleum initiated oil exploration in Qatar. High quality oil

Alfred The Great Research Paper Example | Topics and Well Written Essays - 750 words

Alfred The Great - Research Paper Example King Alfred the Great is said to have quoted â€Å"I desired to live worthily as long as I lived, and to leave after my life, to the men who should come after me, the memory of me in good works." Alfred the Great is best remembered by many historians for his military feats. His victories against the Danes prove his capabilities as a great warrior. He is credited with having built the first royal navy to combat the Danes. Alfred adopted the Danish strategy of building fortified bases. The Danes were defeated by the army of Alfred in May 878 in the Battle of Edington. When Alfred finally managed to defeat the Danes, instead of avenging the attacks, exhibited true statesmanship. He entertained the defeated Danish monarch and signed the Treaty of Wedmore, whereby he accepted the Danish occupation of East Anglia. Wessex was secured for Alfred and this resulted in lasting peace. According to the peace treaty, Guthorn was baptized into the Christian faith and is troops from Wessex. Alfred Recognize the Danish control of East Anglia and a few parts of Mercia. In another treaty signed in 886 called the â€Å"Danelaw† the partition of England was formalized. After this, Alfred began fortifying his kingdom with forts to secure it from invasions. To augment his defenses, Alfred constructed a fleet of ships and thereby came to be famously called the â€Å"Father of the English Navy.† (Britannia) The life of King Alfred is a life of â€Å"quiet virtue and unobtrusive success.† (Alfred the Great: The Truth Teller, Maker of England, 848-899 by Beatrice Adelaide Lees). He does not arouse strong feelings of passion that inspire poetry. Instead he is remembered as a friend of the poor, an ally of the clergy and a scholar king. Being a scholar himself, he is known to have translated many Latin books into the tongue of the Anglo Saxons. One of Alfred’s contemporary works that was left unfinished was a Latin account by Asser, a Welshman who was Alfred’s

Research Methodology Chapter: Communication Research

Research Methodology Chapter: Communication Research One communication-related aspect of the engagement debate concerns the fundamental nature of engagement and whether it can be considered an attitude, a psychological or motivational state, or a personality trait. The nature of engagement is a significant issue for corporate communicators since they are well-placed to influence workplace attitudes and stimulate employee motivation. Kahn (1990) presents engagement as a three-component construct influenced by three psychological states. Robinson et al. (2004) define the concept as a positive attitude. Conversely, Saks (2006) argues that engagement is not an attitude but a psychological state, while others (Sparrow and Balain, 2010) believe that engagement is an attitude. Macey and Schneider (2008a) regard engagement as a complex network encompassing trait, state, and behavioural constructs. Kahn (2010) contrasts his conception of dynamic engagement with steady-state (trait) views of motivation. Kahn describes engagement as both delicate and fragile, and quite resilient. So, Kahns view of engagement exhibits a mixture of attitudinal-type states together with more fixed steady-state predisposition traits. This complex state and trait view of engagement is useful for communicators since it highlights a need for employee communication to understand and serve internal stakeholders core (trait) communication needs, as well as surface (state and attitude) communication needs. Moreover, internal communication represents one of the organisational conditions that facilitate engagement. Pugh and Dietz (2008) consider leadership as a precursor of organisation engagement and organisational effectiveness as a consequence. The communication abilities of leadership teams are recognised as important in driving engagement (Wiley et al., 2010). Communication has been identified also as an underlying factor associated with employee engagement (Kahn, 1992). Likewise, MacLeod and Clarke (2009) highlight communication as a critical factor for enhancing performance through employee engagement. They argue that good quality internal communication enhances engagement as they emphasise that employees need clear communication from senior management to understand how their own roles fit with the organisation vision. Unsurprisingly, they cite poor communication as a barrier to engagement and a cause of disengagement. However, contributions from the professionals on communication disciplines are surprisingly meager given that internal communication is an organisational level interventio n which can positively impact employee engagement. Internal communication in any organisation has been stated to have a correlation with employee feeling of self-satisfaction and their productivity (Clampitt and Downs, 1992). High communication effectiveness is linked to better financial performance and organizational stability (Internal communication effectiveness enhances bottom-line results, journal of organizational excellence, Summer 2006, pp 71-71) Van Riel (1998, pp. 8-27) gives an overview of the elements of corporate communication as all the communication within an organisation, such as managerial communication, organisational communication, and marketing communication. This informs the employees willingness to meet the strategic mission, vision, and objectives of the organisation which creates a competitive advantage of the organisation. Research Design This section will discuss the research framework proposed for use in this study. This methodological framework is influenced by the research onion model develop by Saunders (2012) pp 128 which include general information regarding the research design and strategy, method of data collection, measurement of variable and data analysis as well as evaluate the credibility and validity of the study. There would be an examination of merits and demerits of the chosen methods use in this study, a consideration of ethical issues, as a result, the limitations. Research Design Available literature considers basically five different approaches ranging from experimental, case study, longitudinal, cross-sectional to comparative design (Bryman and Bell, 2011; Saunders et al, 2009). In view of the aim of this research, there will be a combination of approaches also known as a mixed method in the investigation of the research theme (Saunders et al, 2009). Also, a set of quantifiable data will be collected to help establish the relationship between two or more variables (Bryman and Bell, 2011). Research Strategy The strategy to be adopted for this research will be quantitative in nature, this is because will be formulation and testing of hypotheses which are tentative suppositions or proposed explanations made based on limited evidence as a starting point for further investigation which on the face of empirical evidence could hold true or false and as such be graduated to be theory or otherwise. According to Saunders et al, (2009) quantitative research is a strategy that lay emphasis on quantification in data collection and analysis that provides solid scientific fact of knowledge on the basis of positivism. Furthermore, Bryman and Bell, (2011) suggested that the application of a quantitative research strategy has the latent for statistical generalization as against qualitative research employed in many social and natural sciences academic disciplines which are more descriptive. This method of approach, therefore, is more useful to achieve the set aims and objectives of this research stated herein. Data Collection There will be the use of both primary and secondary data collection sources to collect appropriate and relevant data that will enable credible, complete and valid conclusions in accordance with the aims and objectives of the research. Primary data will include the conduct of interview of some members of the management team of the case study organisation and a questionnaire of other concerned employees. The use of these two methods is hoped to balance some of the limitations inherent in each. In addition, this research will use the content analysis approach which is a strategy for the review and analysis of relevant secondary documents from Abellio. Data Analysis All data collected for the purpose of this research will be careful analysis and tested against the theories with the aid of IBM SPSS statistical program. IBM SPSS Statistics is an integrated software product that addresses the entire analytical process, from planning to data collection to analysis, reporting, and deployment (Gaskin, J, 2012). It provides a range of statistical procedures suitable for many problems, including crosstabs, linear regression, Monte Carlo simulation, geospatial analytics, and the ability to extend built-in capabilities with Python, R, or Java code (IBM.com). I have opted for IBM SPSS statistical program for its effectiveness in data analysis and presentation quality of custom tables to help users and analysts to interpret data which could then be tested against the theoretical statements that could, in turn, lead to further generalisation statements (Bryman and Bell, 2011). Limitations of Study The following limitations are anticipated: 1. Data collected is based on interviews and questionnaires administered and as such respondents may not give the actual situation for fear that management of reprisal action against them 2. The data collected by the observation technique may be very limited. 3. The case study organisation has a large number of employees consequently, only one hundred of the affected will be sampled through the rank and file. 4. Equally important is the problem of time as the research will only be conducted within given three-month period. Frankenstein | Analysis Frankenstein | Analysis Frankenstein was a man whose ambition led to a disaster; and his actions led to evil. These are outcomes for which he is solely responsible. Is Frankenstein an innocent? In my opinion, he was not an innocent. The meaning of innocent is to free from evil or guilt. The word Frankenstein is defined in the Encarta dictionary as a creator of something that causes ruin or dest ruction, or brings about a personal downfall, this shows that his name was quite well suited. A common quotation is that One is innocent until proved guilty, If this quotation is applied to Victor Frankenstein, he would be innocent, however my argument is that he was not innocent, it was his fault his family suffered, he brought on his own destruction and was responsible for creating a human, which was morally and contextually incorrect; He would be innocent for allowing the murders of William, Justine, Elizabeth and Clerval to take place. It may be true that Frankenstein did not physically murder, however, he is the main cause, and the reason they died. Frankenstein never admitted to his families what he had done; he never took responsibility for his actions. The so called monster murdered for companionship, not to seek revenge from his victims, but to seek revenge from Frankenstein. The circumstances forced Frankensteins monster to do so, Victor was the instigator of these circumstances. My first thought was to discover what I knew of the murderer and cause instant pursuit to be made. But I paused when I reflected on the story I had to tell, this shows that Victor had the knowledge that he was the reason William was dead. He said my first thought, showing the clearness of his knowledge and that this thought had been lingering in his mind, he knew what he was doing. Frankenstein didnt need to know about the murderer, because he indirectly was the murderer, through the circumstances he created for the monster, as I mentioned briefly before. Which is why he paused half way through his thought and realised he was exactly who the murderer was, even though he blamed the creature. Frankensteins reason for creating the creature was his interest in his studies, which led him to the idea of bettering mankind. Victor thought he was doing a service to humanity by creating a new human. A new species would bless me as its creator and source; many happy and excellent natures would owe their being to me. I might in process of time (although I now found it impossible) renew life where death had apparently devoted the body to corruption. This quote shows his ego behind these plans. He wanted to conquer death, something the average human could not do. He wanted this creature to revere him highly by as he was supposedly beautiful and perfect creature. According to him, it may have been acceptable to play the role of god; maybe his being a scientist is why he didnt think of what was morally correct, and he didnt think of how the society would react to his actions. However, having said that, he didnt admit his doings to his family, perhaps he knew they wouldnt accept it, or the deaths in the family could have a higher weightage in terms of being more important than letting his parents know the truth. If they did know the truth, they wouldnt be happy with him creating the creature. The quote does show that right from the start, Victor had an idea of how he would somewhat be stepping into the shoes of a godlike figure, he outlines the fact that he would be superior, and he would have the power to renew the dead. This proves that he had no innocence, or naivety in terms of knowing precisely what he was doing and what it would lead to. I, the miserable and the abandoned, am an abortion, to be spurned at, and kicked, and trampled on. Is what the creature says after being shunned, on the basis of aesthetics. This shows his faults, and how he was wrong to shun the creature. He may have shunned it because he already conquered death, so in his view, he may have already obtained the status of god, or a superior power, something no one had achieved. He didnt think about anything past the ugliness of the creature, or his personal benefits. His selfishness is what ultimately destroyed him and others as well. The creature he created is more like a project to Frankenstein, his aim is to conquer death, and once he has done so, the project is over. Not once does he consider the fact that he has simply given birth to a new human being, with feelings and emotion, a live creature who has to be taught the ways of life as if it is a baby. Frankensteins abandonment of the creature is another factor that proves him guilty, and not an innocent, as shown in the quote I previously mentioned, with the creatures emotions towards being shunned. Its his own fault that the creature comes back saying I may die; but first you, my tyrant and tormentor, shall curse the sun that gazes on your misery. Beware; for I am fearless, and therefore powerful. The creature was deprived of the companionship, which he could only get from his creator. The creature figures that the only way he can get some attention, is by threatening his creator. This could be compared to a situation with a child and a parent. Frankenstein is somewhat the parent of his creature. His job is to nurture him, but because of his own ego, he runs away. If it were a parent and a child, the child would be defenceless because it hasnt even developed physically, however the creature is an example where he is an uneducated child, with a higher physical strength. Frankensteins creature thinks through intuition, as any child who hasnt learnt anything would do. He doesnt know whats right and wrong, so he doesnt know its wrong to threaten; he doesnt know its wrong to kill. Blaming him is like blaming a child for breaking a valuable, such as a vase. You cant blame the child because their knowledge hasnt developed, they havent yet learnt. However in the childs case, after making such a mistake, the child would be taught not to do so again, creating a basis of how it is wrong, this does not take place for the creature. It could be argued that the creature shou ld know through Victors fear, but does a child learn anything when it senses fear? No, it anything, it will only learn to keep intimidating. Frankensteins faults of his creation, or you could say his faults in parenting, were completely his responsibility. Frankensteins creature is described as having dark black hair, yellow skin, black lips and eyes sunk into his sockets (Shelly 56). Its quite ironic that Frankenstein feared his own creation, he is the one who hand-picked the features his so called perfect man would have. For him to say breathless horror and disgust filled my heart(56), towards a creation of his own, just shows his tendency towards aesthetics, and how backward he is in terms of being accepting, yet how forward he is in terms of doing something new. He is responsible for the way the creature turned out. This once more, proves his irresponsibility, and his view to the creation as a project. His attitude towards the creature is why he was incapable of acting the right way. He wasnt serious enough, or perhaps he wasnt ready to face negative consequences, seeing as he was a perfectionist. The background Frankenstein created in terms of nurture is what caused his creature to murder. Victor admitted to creating the monster, but he denied that he drove the monster to commit murder. He wouldnt admit to anyone; not himself, not his family, that he was the one who allowed the murders to take place. He allowed Clerval, his wife Elizabeth, his brother William and Justines death to take place because he didnt take the blame for his actions. If he had admitted to his actions earlier, less deaths would have been caused, if he had been responsible, and given the creature what it needed, he would not be guilty of four murders. In the end, Frankenstein was at loss of everything close to him, he blamed the monster, but it was his fault. He had a faint idea that it was his fault, although no one could possibly be able to admit to murdering the people close to them. The only way he could be innocent, is for not literally taking a knife and stabbing his relatives. However the pain he got from his creature was his own fault. Innocence lies in having no sense of guilt for any action of yours, this, Victor did clearly not have. The creature couldnt stop himself from destroying Victor, because Victor couldnt stop himself from creating the creature. The creature was an innocent; it only reacted to the actions of society. Victor was guilty in every way. Arrhythmogenic Right Venticular Dysplasia | Case Report Arrhythmogenic Right Venticular Dysplasia | Case Report Arrhythmogenic Right Venticular Dysplasia – A Rare case report from tribal zone of Central India Dr. Prakash Khunte, Dr. P. Beck, Dr. K. Yadav ABSTRACT Arrhythmogenic right ventricular dysplasia (ARVD) is under diagnosed cardiomyopathy which commonly presents in young adults with ventricular tachycardia or sudden death. It is characterized pathologically by progressive fibrofatty replacement of the myocardium, primarily of the right ventricular free wall. Clinically, it presents with life-threatening malignant ventricular arrhythmias which may lead to sudden death, most often in young people and athletes. ARVD/C is difficult to diagnose, although standardized diagnostic criteria have been proposed, based on the presence of major and minor criteria encompassing electrocardiographic, arrhythmic, morphofunctional, histopathologic, and genetic factors. Case report A 30 year male patient named Heeralal Diwakar R/o Baloda Bazar (C.G.) was admitted in department of Medicine, Intensive cardiac Coronary Unit at Pt. J. N. M. Medical College Dr .B.R.A.M. Hospital Raipur with the complain of palpitation ,dizziness, dyspnoea on exertion and left sided chest pain, cough with expectorant distension of abdomen since 8 days.patient having severe palpitation and dizziness in recent hours. Patients having similar complain and admitted two time in hospital in last two year and patient had episode of PSVT and had given DC shock and patient on aspirin,amidaron,metoprolol. There is no family history of sudden cardiac death and any heart disease. Patient was former by occupation and having addiction to tobacco and occasionally alcoholic. On admission patient on general examination pulse -100/min regular.blood pressure was 100/70 mmhg, height -161 cm,weight 58 kg,BMI- 22.39,Iteric ,no cyanosis, oedema were present .on systemic examination bilateral crepitatition present in infrascapular area ,apex beat present on 5 th intercosta space on midclavicular lines,s1 soft.s2 present,s3,s4 absent .No thrill ,murmur,parasternal heave were present. On investigation E.C.G. ST segment elevation seen in lead II,III,aVf, ST segment depression in lead I,Avl,Twave inversion in v1-v6, epsilon wave in V1-v3. Troponin card test was positive and patient diagnosed as acute inferior wall Myocardial Infraction with congestive cardiac failure. Other investigation were random blood sugar was 120 mg/dl, urea 90 mg/dl, creatinine 2 mg/dl,s.billirubin 3.7 mg/dl , direct billirubin 2.3 mg/dl,S.G.O.T S.G.P.T were high,alkaline phosphatase 12877 mg/dl ,sodium 130 mg/dl, potassium 4.9 mg/dl.s. protein 7 g/dl,serum albumin 4 gm/dl,s. cholesterol 114 mg/dl, triglyceride 64 mg/dl,LDL 84 MG/DL,VLDL 13 mg/dl,HDL-17 mg/dl. TLC count were 34000/cumm,Hb 14.5 gm/dl, platelet 222000 /cumm X ray chest cardiomegaly was present. On echocardiography Right ventricle dilated ,RV wall thickness 4 mm. Right Atrium dilated, severe non hypertensive TR , Right ventricle thinned out ,normal LV systolic function suggestive of Arrhythmogenic right ventricular dysplasia. Patient was advised to continue amiodarone ,aspirin ramipril and has been asymptomatic ever since. DISCUSSION The name arrhythmogenic right ventricular dysplasia(ARVD) was coined for the first time in 1978 by Frankand Fontaine. Arrythmogenic right ventricular (RV) cardiomyopathy (ARVC) is a cardiomyopathy characterized pathologically by fibrofatty replacement primarily of the RV and clinically by life-threatening ventricular arrhythmias in apparently healthy young people. The prevalence of the disease has been estimated at 1 in 5,000 individuals, although this estimate will likely increase as awareness of the condition increases among physicians. Arrythmogenic RV cardiomyopathy is recognized as a cause of sudden death during athletic activity because of its association with ventricular arrhythmias that are provoked by exercise-induced catecholamine discharge. Diagnosis may be difficult because many of the electrocardiographic abnormalities mimic patterns seen in normal children, and the disease often involves only patchy areas of the RV. he prevalence of ARVC in the general population is approximately 1 in 5,000 , but the disease is not widely recognized because of the difficulty in making the diagnosis . A familial predilection of the disease has been recognized since 1982 when Marcus et al. described 24 cases of ARVC, two in the same family. Subsequently, several groups have reported familial ARVC, and families with two or more affected individuals have been recognized in Asian, Japanese, Northern European, African and North American populations . Genectics The disease is typically inherited as an autosomal dominant trait with variable penetrance and incomplete expression. The genes responsible for ARVC have not been identified, but seven loci have been mapped to chromosomes 14 (14q23 to q24 and 14q12 to q22), 1 (1q42 to q43), 2 (2q32.1 to q32.2), 3 (3p23) and 10 (10p12 to p14) . The genetic products of these sites have not been easily identified because of incomplete penetrance and expression, age-related expression and difficulties with accurate diagnosis of the disease. Recently, plakoglobin has been identified as the first gene responsible for autosomal recessive ARVC . The gene was identified in Naxos disease where greater than 90% cosegregation of ARVC with cutaneous manifestations, woolly hair and keratodermia, facilitated case identification. Plakoglobin participates in forming cell-to-cell junctions. It is postulated that inadequate cell adherence damages the cardiac cell membranes leading to cell death and fibrofatty replaceme nt. The cardiac ryanodine receptor gene (RyR2) has also recently been implicated in ARVC and offers potential insight into the association of adrenergically mediated ventricular arrhythmias with this disease. The ryanodine receptor induces calcium release from the sarcoplasmic reticulum into the cytosol . The cardiac ryanodine receptor has also been identified as being responsible for catecholamine-induced ventricular tachycardia . Its skeletal muscle counterpart has been implicated in malignant hyperthermia and central core disease , a congenital myopathy, but the mechanisms by which mutations in the cardiac ryanodine receptor might mediate fibrofatty myocardial changes are not clear and will likely be the focus of future studies. Despite these advances, genetic analysis for ARVD is not clinically available and is restricted to research laboratories. Histopathology Characteristically, the RV in ARVC is replaced with a fibrofatty tissue. Morphologic alterations of ARVC usually begin in the subepicardium or mediomural layers of the RV and progress to the endocardium with fibrofatty replacement of myocytes and thinning of the wall. The regions of RV most frequently involved are the RV inflow area, the apex and the infundibulum. These three areas form â€Å"the triangle of dysplasia† . However, small amounts of fat are present in the epicardial layer and within the RV myocardium in normal subjects. Etiology In addition to a genetic cause of ARVC, disontogenetic, degenerative, infectious or inflammatory ( apoptotic and myocyte transdifferentiation theories have been proposed either as the cause of or as environmental factors facilitating gene expression. The disontogenetic theory is largely historical but suggests that ARVC is a milder form of â€Å"parchment RV† or Uhl’s anomaly a congenital hypoplasia of the RV myocardium, which presents in infancy as congestive heart failure (CHF) . The degenerative theory suggests that ARVC is a consequence of myocyte death due to an inherited metabolic or ultrastructural defect. A possible defect has been mapped to chromosome l4q23 to q24 . This area encodes for the alpha actinin gene, which shares structural homology with the amino terminal domain of dystrophin. This finding supports the concept of a genetically determined atrophy similar to that in patients with Duchenne’s or Becker’s muscular dystrophy. Some have suggested that ARVC should be considered as a â€Å"myocardial dystrophy† Furthermore, skeletal muscle involvement has been reported in a Swedish family with ARVC, and the defect has been tentatively localized to chromosome 10q22.3 The infectious or inflammatory theory maintains that the disease results from previous myocarditis. Inflammatory infiltrates are common in histologic specimens from patients with ARVC ECG The ECG in patients with ARVD/C usuallyshows sinus rhythm, QRS duration 110 ms in lead V1, a terminal deà ¯Ã‚ ¬Ã¢â‚¬Å¡ection within or at the end of the QRS complex (called epsilon wave) in leads V1–V3 (30% of patients), and inversion of T waves in the right precordial leads (50%–70% of patients). Complete right bundle branch block is found in approximately 15% of patients and incomplete right bundle branch block in 18% of patients with ARVD/C. In the presence of right bundle branch block pattern, selective prolongation of the QRS duration in leads V1–V3 compared with lead V6 (25 ms, parietal block) is an important hallmark of ARVD/C. . Additional ECG markers have been reported, such as the ratio of QRS duration in leads V1V2V3 vs V4V5V6 >1.2 and a prolonged S wave upstroke in V1–V3 >55 ms in the absence of right bundle branch block. Arrhythmia Left bundle branch block type VT on ECG, Holter monitoring, or during exercise testing Extrasystoles of more than 200 over a 24-h period. Echocardiography mild to Severe dilatation and reduction of right ventricular ejection fraction with no (or only mild) left ventricular impairment Localised right ventricular aneurysms (akinetic or dyskinetic areas with diastolic bulging) Severe segmental dilatation of the right ventricle. Radioisotope techniques Radionuclide angiography, by showing abnormal right ventricular function with left ventricular involvement, is usefulfor predicting subsequent cardiac death in ARVD/C.Myocardial perfusion scintigraphy allows noninvasive assessment of right ventricular damage in patients with arrhythmias due to ARVD/C This technique may distinguish patients with ARVD/C from those with idiopathic right ventricular outà ¯Ã‚ ¬Ã¢â‚¬Å¡ow tract tachycardias Cardiovascular magnetic resonance imaging This modality allows visualization of the right ventricle, not only anatomically and morphologically but also in functional and à ¯Ã‚ ¬Ã¢â‚¬Å¡ow dynamic terms. Functional ab normalities consist of right ventricular aneurysms, regional thinning, right ventricular dilation, failure of systolic thickening, and impaired global and diastolic right ventricularfunction. Clinical presentation The clinical presentation varies widely because ARVD/C includes a spectrum of different conditions rather than a single identity. Different pathologic processes may manifest a diversity of symptoms, such as fatigue, atypical chest pain, syncope, or acute coronary syndrome .ARVD/C is a disease that may have a temporal progression, and the disease may present differently according to the time of presentation There may be (1) a symptomatic form with transient or sustained ventricular tachycardia of left bundle branch block configuration, although right bundle branch block configuration also can be observed; (2) an asymptomatic form consisting of ventricular ectopic beats (1,000/24 hours); (3) right ventricular failure with or without arrhyth mias; and (4) a masked form in which sudden death, usuallyduring exercise, is the first clinical presentation. Overall, judging the accurate position of the patient on the time scale of the spectrum is difficult, and some patients may remain stable for several decades. Diagnosis A definite diagnosis of ARVD/C is based on histologic demonstration of transmural fibrofatty replacement of right ventricular myocardium at either autopsy or surgery. In 1994, McKenna et al established the criteria for diagnosing ARVD/C in a Task Force report on ARVD/C Criteria for Diagnosis of ARVD/C 1. Family history Major Familial disease confirmed at necropsy or surgery. Minor Family history of premature sudden death (,35 years of age) due to  suspected ARVD/C. Family history (clinical diagnosis based on present criteria). 2. ECG depolarization/conduction abnormalities Major Epsilon waves or localized prolongation (.110 ms) of QRS complex in  right precordial leads (V1–V3). Minor Late potentials on signal-averaged ECG. 3. ECG repolarization abnormalities Minor Inverted T waves in right precordial leads (V2 and V3) in people. 12  years of age and in absence of right bundle branch block. 4. Arrhythmias Minor Sustained or nonsustained left bundle branch block–type ventricular  tachycardia documented on ECG or Holter monitoring or during  exercise testing. Frequent ventricular extrasystoles (.1000/24 h on Holter monitoring). 5. Global or regional dysfunction and structural alterations* Major Severe dilatation and reduction of RV ejection fraction with no or mild  LV involvement. Localized RV aneurysms (akinetic or dyskinetic areas with diastolic  bulgings). Severe segmental dilatation of RV.   Minor Mild global RV dilatation or ejection fraction reduction with normal LV. Mild segmental dilatation of RV. Regional RV hypokinesia. 6. Tissue characteristics of walls Major Fibrofatty replacement of myocardium on endomyocardial biopsy. *Detected by echocardiography, angiography, magnetic resonance imaging,  or radionuclide scintigraphy. Modified from McKenna et al. Therapy Because clinical findings that predict long-term outcomeof patients with ARVD/C are incompletely known, no precise guidelines exist to select patients who should be treated with b-blockers, antiarrhythmic drugs, or a Implantable cardioverter-defibrillator. r. Management of patients with ARVD/C is individualized, and strategies are based on local experience of the different centers. References Siddiq I. Khalil), Amjad Kamal, Shakeel Ahmad Department of Medicine and Cardiology, Almana General Hospital, PO Box 10366,Jubail 31961, Saudi Arabia. Eur J Echocardiography (2004) 5, 394e398. Carol Gemayel, MD*; Antonio Pelliccia, MD† ; Paul D Thompson, MD J Am Coll Cardiol. 2001;38(7):1773-1781.doi:10.1016/S0735-1097(01)01654-0. Cristina Basso, Domenico Corrado, Frank I Marcus, Andrea Nava, Gaetano Thiene Lancet 2009; 373: 1289–1300 University of Padua Medical School, Padua, Italy. Philippine Kià ¨s, MD, Marianne Bootsma, MD, PhD, Jeroen Bax, MD, PhD,  Martin J. Schalij, MD, PhD, Ernst E. van der Wall, MD, PhD Heart Rhythm, Vol 3, No 2, February 2006,Department of Cardiology, Leiden University Medical Centre, Leiden, The Netherlands. Domenico Corrado, Guy Fontaine, Frank I. Marcus, William J. McKenna, Andrea Nava, Gaetano Thiene and Thomas Wichter, Circulation. 2000;101:e101-e106, doi: 10.1161/01.CIR.101.11.e101 Frank R, Fontaine G. Electrocardiologie de quatre cas de dysplasia ventriculaire droite arythmogene. Arch Mal Coeur Vaiss 1978;71:963–972. Rampazzo A, Nova A, Malacrida S, Beffagua G, Bauce B, Rossi V, et al. Mutation in human desmoplakin domain binding to plakoglobin causes a dominant form of arrhythmogenic right ventricular dysplasia. Am J Hum Genet 2002;71(5):1200e6 Bauce B, Rampazzo A, Basso C, Bagattin A, Daliento L, Tiso N, et al. Screening of ryanodine receptor type 2 mutations in families with effort induced polymorphic ventricular rhythmias and sudden death: early diagnosis of asymptomatic carrier. JACC 2002;40(2):341e9.

As Good As It Gets?: An Examination Of The Mechanism And Mode Of Treatm

As Good As It Gets?: An Examination Of The Mechanism And Mode Of Treatment Of Obsessive-Compulsive Disorder Obsessive-compulsive disorder, often referred to as simply OCD, is a mental illness in which an individual experiences endless cycles of repeated thoughts and rituals, known as obsessions and compulsions, which she feels she cannot control (1). Although many people possess habits and routines that help them organize their every day schedules, people with OCD form patterns of behavior that are extremely time-consuming and interfere with their daily lives. Once believed to be a rare and incurable disease which people kept hidden for fear of embarrassment (2), OCD is now recognized as being far more common than previously believed, affecting both men and women, and people of all races and socio-economic backgrounds equally (3). In fact, recent studies have shown that about 2.5% of the population have this disorder at some point in their lives (2), with between 3 to 5 million Americans affected with the disorder each year (3). Though OCD is a chronic illness that can take over a person's life if left untreated (1), a strict regiment involving proper medication and effective treatment can vastly improve the OCD sufferer's condition. Obsessive-compulsive disorder is composed of two major constituents evident in its very name - obsessions and compulsions. Obsessions are recurring thoughts or impulses that seem to invade one's mind despite attempts to ignore or suppress them (4). Though these thoughts range from the tedious and seemingly innocuous sort, to the shameful and morbid kind, all are generally viewed as senseless and are accompanied by anxiety to some degree (4). Some common examples of obsessions include: fe... ...tion remains an option. Regardless of whether an OCD patient is treated in or out of a hospital, treatment is vital in improving his condition, for if left untreated, the disorder will continue indefinitely (3). With the wide range of treatment options available to OCD sufferers and the extensive studies being conducted in lieu of the disorder, the promise of a future with less worries and anxiety appears to be well within reach. WWW Sources 1) Obsessive-Compulsive Disorder , on the National Institute of Mental Health website http://www.nimh.nih.gov/anxiety/ocdfacts.cfm 2) Obsessive-Compulsive Disorder: What Is It and How To Treat It http://familydoctor.org/133.xml 3) Most Frequently Asked Questions About OCD http://www.ocdhelp.org/faq.html 4) Obsessive-Compulsive Disorder , on the Encyclopaedia Britannica website http://www.britannica.com/